How many of your patients right now have both MCAS (mast cell activation syndrome) and POTS (postural orthostatic tachycardia syndrome)? Many I’m sure! Have you determined which came first? You…
Summary & Contents The cell danger response (CDR) is a cellular-initiated threat involving the signaling of extracellular nucleotides such as ATP and ADP Extracellular ATP is a potent purinergic signaling…
Summary & Contents The extracellular matrix is comprised of electrolytes, glycosaminoglycans, polysaccharides, collagen & proteins The extracellular matrix is essential for how cells function through the regulation of the cell’s life cycle,…
Individuals with joint hypermobility often present with complex symptom presentations, including: MCAD (mast cell activation disorders), POTS (postural orthostatic tachycardia syndrome), PTSD (post traumatic stress disorder), autoimmune diseases and dysautonomia,…
Ehlers danlos syndrome, commonly referred to as EDS is a vastly under-diagnosed connective tissue disorder in the human population. EDS is classified as having at least 13 different subtypes, and there is much…
Histamine is a powerful molecule. When it is activated, it has numerous physiological effects through its various histamine receptors. Understanding the various roles that histamine occupies, confers new insights into the implications…
High histamine has now become a centrally important topic in the health world. Previously I’ve reported that not only is histamine an inflammatory immune response mediator, its also a neurotransmitter that may…
If you think that high histamine is only an issue during allergy season, think again. Most people are completely unaware that histamine facilitates a central role in: Brain & neurotransmitter…