CIRS is also known as ‘chronic inflammatory response syndrome’. CIRS is a term that was created by Ritchie Shoemaker, MD (11) out of the necessity to define the pathology of biotoxin and mold-related illness. CIRS is based upon a series of inflammatory responses to biotoxin exposure, such as mold exposure from water-damaged buildings (11, 12).
Individuals with joint hypermobility often present with complex symptom presentations, including: MCAD (mast cell activation disorders), POTS (postural orthostatic tachycardia syndrome), PTSD (post traumatic stress disorder), autoimmune diseases and dysautonomia, endometriosis, ovarian cysts, ME/CFS, mental and behavioral conditions and emotional and sensory processing disorders. Variability of the RCCX cluster provides a very appealing and viable
Ehlers danlos syndrome, commonly referred to as EDS is a vastly under-diagnosed connective tissue disorder in the human population. EDS is classified as having at least 13 different subtypes, and there is much confusion as to the relationship with other connective tissue disorders. The implications for EDS are vast, and extend into areas of immunology, endocrinology, neurology, cardiology, mitochondrial