Autoimmune Thyroid, Danger Signaling & Innate Immune Activation

The origins of autoimmune thyroid disease should be appropriately viewed from the context of immunological dysregulation, set forth by a myriad number of genetic and epigenetic factors. This view should seek to investigate the metabolic significances of thyroid physiology, with its highly oxidative environment, as well as its propensities towards heightened danger signaling and innate

CYP21a2, RCCX & Adrenal Function: A Completely Different Perspective

The label “adrenal fatigue” has been debated and deconstructed, endlessly for decades. Adrenal fatigue, or adrenal burnout is a term used by alternative healthcare practitioners as an attempt to make sense of an array of symptoms pertaining to fatigue, exhaustion, and everything that is associated with those symptoms. Practitioners utilize various cortisol hormone tests, as

RCCX: A Link to Complex Illness & Why Its Important

Individuals with joint hypermobility often present with complex symptom presentations, including: MCAD (mast cell activation disorders), POTS (postural orthostatic tachycardia syndrome), PTSD (post traumatic stress disorder), autoimmune diseases and dysautonomia, endometriosis, ovarian cysts, ME/CFS, mental and behavioral conditions and emotional and sensory processing disorders. Variability of the RCCX cluster provides a very appealing and viable

Hyper Joint Mobility, EDS, Collagen, Histamine & CIRS: Implications

Ehlers danlos syndrome, commonly referred to as EDS is a vastly under-diagnosed connective tissue disorder in the human population. EDS is classified as having at least 13 different subtypes, and there is much confusion as to the relationship with other connective tissue disorders. The implications for EDS are vast, and extend into areas of immunology, endocrinology, neurology, cardiology, mitochondrial

Iron Deficiency & Hypothyroidism: Common Patterns

Hypothyroidism and subclinical hypothyroidism are very common presentations in today’s world. Essentially there are 2 forms of low thyroid function: autoimmune hypothyroidism and non-autoimmune hypothyroidism. Because thyroid hormone is essential to every cell of the body, decreases in thyroid function may result in an array of symptoms and altercations to many bodily systems and functions.