Research on PCOS (polycystic ovarian syndrome) has been focusing on mechanisms to control insulin resistance, androgen excess and hormonal signaling problems that are characteristic presentations leading to symptoms and complications.
Is it possible that isomer forms of the vitamin Inositol are efficacious in PCOS? Research has recently been published demonstrating the effects of myo-inositol (as opposed to regular inositol or D-chiro inositol) at modulating FSH, and improving ovarian gonadotrophin sensitization (1).
The effect of myoinositol appears to be different than the effects of D-chiro inositol, which has shown to modulate insulin sensitization.
These distinctions in the isomeric actions of inositol are significant, because PCOS etiologies can present differently in women. It is quite clear that a significant percentage of women with PCOS do not have insulin resistance. These women would benefit by modulating FSH, LH, androgens as well as aromatization of androgens into estrogens. Myoinositol may be one major go-to to help engage the process of gonadotrophin signaling.