The origins of autoimmune thyroid disease should be appropriately viewed from the context of immunological dysregulation, set forth by a myriad number of genetic and epigenetic factors. This view should seek to investigate the metabolic significances of thyroid physiology, with its highly oxidative environment, as well as its propensities towards heightened danger signaling and innate
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The label “adrenal fatigue” has been debated and deconstructed, endlessly for decades. Adrenal fatigue, or adrenal burnout is a term used by alternative healthcare practitioners as an attempt to make sense of an array of symptoms pertaining to fatigue, exhaustion, and everything that is associated with those symptoms. Practitioners utilize various cortisol hormone tests, as
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RCCX is a copy number variation (CNV) gene cluster located on chromosome 6. Variations of the RCCX genotype leads to an increased susceptibility to numerous diseases. Significant research links together one of the RCCX genes, C4b with autism, associated cell danger signaling, and problems related to neuronal, synaptic pruning. Last year I wrote an article
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One of the major complications of CIRS and mold illness is a type of sinus infection known as marcons. Marcons stands for Multiple Antibiotic Resistant Coagulase Negative Staphylococci. Marcons is a type of staph bacteria that produces a biofilm, making it difficult to eradicate. in addition to resulting in sinusitis symptoms, marcons is believed to complicate
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BCL-2 is a key protein inside cells that functions as a type of control switch for cell-programmed death, known as apoptosis. Significantly, cancer cells are locked in a malignant state of cell division, where apoptosis genes are down-regulated or switched off. Over-expression of BCL-2 in cancer cells is associated with the inability of cancer cells
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The medicinal properties of fungi are well established. The primary immune-activating constituents include various polysaccharides, including beta glucans, mannans and lectins. The effects of these polysaccharides have far-reaching possibilities for various aspects of the human immune system, including those relating to innate, complement immunity. Polysaccharides & The Complement Immune System The complement immune system is
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It is now becoming clear that attempting to test for and correct Vitamin D deficiencies is far more involved than simply looking at levels of 25-hydroxyvitamin D and using supplemental Vitamin D3. That approach fails to recognize the fact that many factors will mediate how 25-hydroxyvitamin D is converted into the active secosteroid hormone Calcitriol
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I have previously reported on the issue of glutamate excitotoxicity. This article is a brief exploration of GAD1, an important gene that is involved in the conversion of the excitatory neurotransmitter glutamate into the inhibitory neurotransmitter GABA. The issue of glutamate toxicity is well understood. In essence, glutamate can result in cell programmed death when
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Lactobacillus reuteri is perhaps one of the most intriguing and significant beneficial microorganisms in the human gut lining. It has been studied as a key modulator of the intestinal immune system, and has even been studied as a regulator of the TH-helper cell response, which is a key component of the autoimmune process. The therapeutic
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In our fast paced, technologically-maximized society, I stand off to the side and ask some serious questions: • Why is the health of our planet and the human race so compromised? • Why are chronic diseases now epidemic? • What are the major causes of chronic disease? • Why has the western medical system failed
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