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The Extracellular Matrix: Key To Unravelling Chronic Disease?

UncategorizedBy Michael E. McEvoy September 23, 2017 1 Comment

Summary & Contents The extracellular matrix is comprised of electrolytes, glycosaminoglycans, polysaccharides, collagen & proteins The extracellular matrix is essential for how cells function through the regulation of the cell’s life cycle, cytoskeletal signaling, growth factor maturation and utilization, cytokine and immune cell recruitment and modulation Toxins like mercury, mold, aluminum, glyphosate and drugs like fluoroquinolones can

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Bone Broth, Collagen & Glyphosate Toxicity

UncategorizedBy Michael E. McEvoy August 21, 2017 4 Comments

Bone broth and collagen supplements are often recommended for healing purposes. While much nutritional benefit may be obtained through bone broth and collagen, there are increasing concerns regarding the toxicity of GMO feeds, the use of glyphosate-containing pesticides on crops, and the inadvertent ingestion of glyphosate through consuming bone broth and collagen supplements or foods.

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RCCX: A Link to Complex Illness & Why Its Important

UncategorizedBy Michael E. McEvoy June 13, 2017 1 Comment

Individuals with joint hypermobility often present with complex symptom presentations, including: MCAD (mast cell activation disorders), POTS (postural orthostatic tachycardia syndrome), PTSD (post traumatic stress disorder), autoimmune diseases and dysautonomia, endometriosis, ovarian cysts, ME/CFS, mental and behavioral conditions and emotional and sensory processing disorders. Variability of the RCCX cluster provides a very appealing and viable

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Hyper Joint Mobility, EDS, Collagen, Histamine & CIRS: Implications

UncategorizedBy Michael E. McEvoy May 5, 2017 Leave a comment

Ehlers danlos syndrome, commonly referred to as EDS is a vastly under-diagnosed connective tissue disorder in the human population. EDS is classified as having at least 13 different subtypes, and there is much confusion as to the relationship with other connective tissue disorders. The implications for EDS are vast, and extend into areas of immunology, endocrinology, neurology, cardiology, mitochondrial

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Essential Thrombocytosis: Effective Alternative Treatments

UncategorizedBy Michael E. McEvoy April 26, 2017 Leave a comment

One of the myoproliferative diseases known as essential thrombocytosis (aka essential thrombocythemia, and essential thrombocythaemia) is a potentially fatal condition that involves the overproduction of blood platelets. New clinical evidence has emerged that shows an assortment of herbal medicines are effective at significantly reducing blood platelets, and with negligible toxicity. What Is Essential Thrombocytosis? Also known

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PCOS & Myoinositol: Does it Work?

UncategorizedBy Michael E. McEvoy April 20, 2017 Leave a comment

Research on PCOS (polycystic ovarian syndrome) has been focusing on mechanisms to control insulin resistance, androgen excess and hormonal signaling problems that are characteristic presentations leading to symptoms and complications. Is it possible that isomer forms of the vitamin Inositol are efficacious in PCOS? Research has recently been published demonstrating the effects of myo-inositol (as opposed

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Estrogen Dominance: Viruses & Autoimmune Disease

UncategorizedBy Michael E. McEvoy April 18, 2017 1 Comment

Summary 78% of people with autoimmune disease are women The rate of Hashimoto’s thyroiditis is 7X more likely to occur in women than men Lower estrogen increases CD8 lymphocytes, which is central to activation of TH1 inflammatory immunity and viral defense Evidence from mice suggests Estradiol medication can reactivate HSV-1 (herpes simplex-1) EBV (epstein barr virus)

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High Histamine Rollercoaster: Implications of This Potent Neuro-Immune Modulator

UncategorizedBy Michael E. McEvoy September 21, 2016 2 Comments

Histamine is a powerful molecule. When it is activated, it has numerous physiological effects through its various histamine receptors. Understanding the various roles that histamine occupies, confers new insights into the implications for dietary, immunological, gastro-intestinal, cardiovascular, endocrinological, neurological, and inflammatory mechanisms. 4 histamine receptors have been identified, and each exert different effects. Histamine is released by

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Are Copper Fungicides Used on Organic Produce Safe?

UncategorizedBy Michael E. McEvoy September 18, 2016 Leave a comment

Copper is a necessary trace element for human health. However, in its free, unbound and oxidized state, copper can act as a pro-oxidant and toxic element. Copper fungicides are an “allowable” chemical that can be used on organic food crops. Organically grown produce may contain copper residues from copper fungicide usage. The presence of copper

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Detoxification of Estrogen: Environment, Genetics & Nutritional Intervention

UncategorizedBy Michael E. McEvoy August 23, 2016 1 Comment

Estrogen dominance is a term that has been used to describe the overload of estrogen. Estrogen overload can be problematic for a number of reasons. For women, excess estrogen activity can alter the menstrual cycle, leading to complications such as PMS. In more extreme scenarios, excess estrogen can lead to conditions such as endometriosis, cancer,

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