The PON1 genotype Q192R, risk allele ‘C’ is now considered a ‘high impact’ genotype that significantly increases cardiovascular disease risk. This article is an attempt to underscore the importance of PON1 and its associated antioxidant functions in the prevention of heart disease. We will cover some major literature on PON1, including genetics, the influence of
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Type 2 diabetes is a multi-factorial condition characterized by chronically elevated blood glucose. While a wide variety of different dietary strategies have been trialed, studied and evaluated, there is a greater need to develop more targeted and individualized dietary treatments, tailored to each patient. Metabolic Type Nutrition is a type of evaluation of dietary and
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Nattokinase is a fibrinolytic enzyme derived from Japanese Natto, a fermented soy food. Accumulating research identifies nattokinase as a potent anti-fibrinolytic and anti-thrombotic agent, serving as a potential treatment for: cardiovascular disease, hypertension, myocarditis, chronic kidney disease and beyond. A 2022 study involving 1,062 heart disease patients in China found high doses of nattokinase significantly
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Emerging scientific research is leading to breakthroughs in the understanding of albumin, the most abundant serum protein. This research links together many of albumin’s diverse roles in human physiology and disease states. This includes albumin’s critical roles in: redox and antioxidant biology, acute inflammation, hemostasis, osmotic fluid regulation, and cellular energy metabolism. This article is
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NFE2L2 is the gene that codes for the NRF2 nuclear transcription factor. Nuclear transcription factors comprise a family of genes that each control the expression of numerous target genes. NRF2 is normally ubiquinated and inactive within the cytoplasm of cells. Under conditions of cellular stress, NRF2 becomes activated and mobilizes to the nucleus, where it
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The APOE 4/4 genotype (often referred to in literature as “APOE homozygotes” or APOE -/-) carry a significantly increased risk of Alzheimer’s disease and cardiovascular disease. By understanding the deeper science of the APOE gene, it may be possible to procure treatment protocols and support the body where it may be lacking. Functions of the
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Preeclampsia in pregnancy is defined by systolic blood pressure levels greater than 140 or diastolic pressure greater than 90. In addition to elevations in blood pressure, other common clinical findings of preeclampsia may include: proteinuria (elevated urinary protein), elevated liver enzymes, edema (fluid retention), headaches and visual disturbances. Preeclampsia can cause several pregnancy complications, including
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The use of iron for anemia may be the wrong approach and even dangerous in some instances. During inflammation and immunological signaling, the body’s utilization of iron can be shifted from constructive processes to destructive. In cases where anemia is caused by the acute phase and inflammation, the objective should be the restoration of the
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In a 1992 patent by Emanuel Revici, MD, heptanoic acid is referenced as a viable treatment for AIDS (1). Accordingly, 3 odd-carbon fatty acids are discussed, pentanoic (C-5), heptanoic (C-7), and nonanoic (C-9). According to this patent, Revici claims that these 3-odd carbon fatty acids (especially heptanoic) “exhibit not only anti-HIV virus effects, but also
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Systemic Lupus Erythematosus (SLE) is a rheumatic autoimmune disease. Heal your body. Learn the best tests, genetic information, natural treatments, lifestyle factors and supplements. Systemic Lupus Erythematosus or SLE is a potentially life threatening, rheumatic autoimmune disease. This article serves as a resource for individuals who would like to understand the most important testing, genetic
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