Estrogen is a necessary cofactor in the biosynthesis of phosphatidylcholine. Women with low estrogen may be at risk for phosphatidylcholine deficiency. Choline & Estrogen: Menopausal Links In summary: In females, estrogen is a cofactor in the function of PEMT, a gene that biosynthesizes the phospholipid, phosphatidylcholine Due to lower estrogen, post menopausal women may have
Get more than ancestry out of your 23andMe test results. Explore your genetic strengths and weaknesses and biohack your way back to health. Turn your 23andMe Raw Data File into a Massive Biohacking Expedition Explore your genome Find your weak genetic pathways Reduce your inflammation Learn new ways of using nutritional supplements and herbs Do
Lyme disease can cause a disruption to collagen. This can lead to many symptoms. Optimize Lyme disease treatments: support your collagen and connective tissue. Lyme disease and associated co-infections have become a pervasive epidemic. More than 300,000 cases of Lyme disease are diagnosed annually in the US, and these numbers are likely significantly under-reporting the
How many of your patients right now have both MCAS (mast cell activation syndrome) and POTS (postural orthostatic tachycardia syndrome)? Many I’m sure! Have you determined which came first? You absolutely should. Why? Numerous antihistamine drugs are also anticholinergics. POTS is characterized by dysautonomia and an associated loss of vagus nerve function. If POTS developed
The RCCX gene cluster on chromosome 6 is one of the most complex regions of the human genome, and one that is likely a major player in chronic disease susceptibility. The RCCX gene region features a series of highly complex and anomalous activities, while the constituent genes in the region confer powerful effects throughout the
Gilbert’s syndrome is a condition involving a genetic polymorphism in a phase 2 glucuronidation gene known as UGT1a1. The result of this causes elevations in the levels of unconjugated bilirubin. The current scientific consensus is that Gilbert’s is a relatively benign condition, that only features elevations of bilirubin. I strongly disagree with that contention. A
CIRS is also known as ‘chronic inflammatory response syndrome’. CIRS is a term that was created by Ritchie Shoemaker, MD (11) out of the necessity to define the pathology of biotoxin and mold-related illness. CIRS is based upon a series of inflammatory responses to biotoxin exposure, such as mold exposure from water-damaged buildings (11, 12).
The origins of autoimmune thyroid disease should be appropriately viewed from the context of immunological dysregulation, set forth by a myriad number of genetic and epigenetic factors. This view should seek to investigate the metabolic significances of thyroid physiology, with its highly oxidative environment, as well as its propensities towards heightened danger signaling and innate
The label “adrenal fatigue” has been debated and deconstructed, endlessly for decades. Adrenal fatigue, or adrenal burnout is a term used by alternative healthcare practitioners as an attempt to make sense of an array of symptoms pertaining to fatigue, exhaustion, and everything that is associated with those symptoms. Practitioners utilize various cortisol hormone tests, as
RCCX is a copy number variation (CNV) gene cluster located on chromosome 6. Variations of the RCCX genotype leads to an increased susceptibility to numerous diseases. Significant research links together one of the RCCX genes, C4b with autism, associated cell danger signaling, and problems related to neuronal, synaptic pruning. Last year I wrote an article