Parasites Lost: Helminths, Pleiotropy, and The Prevention of Dementia

This article was originally published by Holistic Primary Care, Volume 22 No.4; November, 2021. The Holistic Primary Care published article can be viewed at this link. Our ability to link specific genetic features with particular diseases is among molecular biology’s greatest achievements. But there’s a downside to that scientific triumph: it has oversimplified the picture

Maladaptive Genetics: Evolutionary Mismatches, Helminthic Therapy & Complex Disease in the Modern Era

The concept of Evolutionary Mismatches was first expounded on by Ernst Mayr in the 1940’s. That is, certain inherited traits that were once advantageous have become maladaptive in a different or changed environment. The concept of Evolutionary Mismatch is central to understanding the genetic involvement with the rising tide of complex, chronic disease in the

Biological Plasticity, Cell Danger Signaling & Symptom Management: Where To Draw the Line?

There’s a fine balance between treatment and non-treatment. Philosophically I verge more on the side of conservative and “less is more treatment” for many reasons. My current philosophy in these regards is based upon the potential adverse effects of pharmaceuticals, and of the assault I believe many drugs have on memory-based physiological processes, also known

Neurosteroid Hormones & Multiple Sclerosis: A Viable Consideration for Men & Women

Neurosteroids are defined as any steroidal hormone that is permitted to enter the brain and nervous system, or can be produced by those cells. Estrogens, testosterone, progesterone, DHEA, cortisol, allopregnanolone are all neurosteroids, and as such confer potential therapeutic opportunities for neurodegenerative and deymyelinating diseases, such as multiple sclerosis. Scientific Evidence for Neurosteroid Use in