Circadian Biology & Parkinson’s Disease: The Clock is Ticking

Parkinson’s disease involves significant disruption to the circadian clock. A loss of normal clock gene expression leads to a desynchronization of fundamental biological and physiological processes. These findings open the door for circadian rhythm-based treatments for neurological diseases such as Parkinson’s. Parkinson’s disease is characterized as a loss of dopaminergic neurons within the substantia nigra